Association Between Thyroid Disorders And Cardiac Troponins

Abstract

Background: Thyroid dysfunction has been linked to various cardiovascular abnormalities, including changes in cardiac biomarkers. Cardiac troponins, which indicate myocardial injury, have been studied for their potential association with thyroid disorders, but findings remain inconclusive. Objective: To determine the association between thyroid Disorders and cardiac troponins. To investigate the impact of thyroid disorders on cardiac troponin levels and assess their potential role in diagnosing cardiac conditions. Methodology: Data were collected from Galaxy Diagnostic Laboratory and Al Zahid Laboratory, including 30 participants (24 males, 6 females). Thyroid function tests (TSH, T3, and T4) were analyzed, and cardiac troponin I levels were measured to assess myocardial injury. The results were categorized based on thyroid hormone levels and examined for potential correlations. Results: Out of 30 participants, 26 (86.7%) had normal thyroid function, while 4 (13.3%) had elevated TSH levels, indicative of hypothyroidism. Among those with hypothyroidism, 3 were female. Despite abnormal thyroid function in some individuals, all participants tested negative for troponin I, indicating no direct myocardial injury. The mean T3 and T4 levels remained within normal limits, while TSH was significantly elevated in hypothyroid individuals. Conclusion: This study suggests that thyroid dysfunction, particularly subclinical hypothyroidism, does not directly lead to myocardial injury detectable by troponin I. Although thyroid disorders are associated with long-term cardiovascular risks, they do not independently cause acute myocardial injury. Routine thyroid function assessment may be valuable in cardiovascular risk evaluation, particularly in women and individuals with thyroid abnormalities. Further research with larger sample sizes and high-sensitivity troponin assays is recommended to explore subtle cardiovascular effects.

Key words: Thyroid dysfunction, Subclinical hypothyroidism cardiac troponins, myocardial injury, TSH, T3, T4.