Synthesis of Polyvinyl pyrrolidone Nanoparticle and its Antimicrobial Susceptibilities Against Gram-Negative and Gram-Positive Bacteria
DOI:
https://doi.org/10.63075/43zsq722Keywords:
Polyvinylpyrrolidone, Nanoparticle, Antimicrobial Susceptibilities, Gram-Positive BacteriaAbstract
The proliferation of antibiotic-resistant microorganisms necessitates the development of new antimicrobials. Nanoparticles of strontium oxide (SrO) and polyvinylpyrrolidone (PVP) were synthesised, characterised, and shown to be effective against Escherichia coli and Staphylococcus aureus in this investigation. The research of strontium oxide nanoparticles made by co-precipitation was conducted using SEM, XRD, EDX, UV, and FTIR. There was an evaluation of antibacterial activity at 25% and 50% PVP strontium oxide concentrations using the Kirby-Bauer disc diffusion technique. With a 35-mm inhibition zone, a 50% concentration showed modest activity against E. coli and excellent antibacterial efficacy against S. aureus. These results raise the possibility that PVP nanocomposites containing SrO oxide have antibacterial properties, especially when applied to gram-positive bacteria.
